ORCID ID: https://orcid.org/0000-0002-7811-3932 

• Schweizerische Gesellschaft für Rechtsmedizin 
• The International Association of Forensic Toxicologists
• Society of Toxicological and Forensic Chemistry        
• Swiss Group for Mass Spectrometry 
• Swiss Society of Clinical Pharmacology & Toxicology

van der Velpen V, Liakoni E, Hirt MB, Vonwyl CM, Christen SE, Duthaler U, Jacob P, Haschke M. A validated single-step saliva and serum sample extraction LC-MS/MS method for the analysis of nicotine, cotinine and 3'-hydroxycotinine for clinical vaping studies. J Pharm Biomed Anal. 2025 Jun;258:116703. doi: 10.1016/j.jpba.2025.116703

Duthaler U, Chapuisat F, Hanimann R, Krähenbühl S. Effect of protein binding on the pharmacokinetics of the six substrates in the Basel phenotyping cocktail in healthy subjects and patients with liver cirrhosis. Eur J Pharm Sci. 2024 Nov;202:106885. doi: 10.1016/j.ejps.2024.106885

Kamau Y, Tuwei M, Wanjiku C, Ominde K, Ngama M, Karisa J, Babu L, Muturi M, Mwatasa M, Adetifa J, Kern C, Duthaler U, Hammann F, Rabinovich R, Chaccour C, Maia MF. Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial. Int J Infect Dis. 2024 Nov;148:107236. doi: 10.1016/j.ijid.2024.107236

Holze F, Madsen MK, Svarer C, Gillings N, Stenbaek DS, Rudin D, Duthaler U, Liechti ME, Fisher PM, Knudsen GM. Ketanserin exhibits dose- and concentration-proportional serotonin 2A receptor occupancy in healthy individuals: Relevance for psychedelic research. Eur Neuropsychopharmacol. 2024 Nov;88:43-48. doi: 10.1016/j.euroneuro.2024.07.003

Walz A, Lehmann U, Duthaler U, Mäser P, Wittlin S. In vivo antimalarial efficacy of Artemisia afra powder suspensions. Phytomedicine. 2024 Jul;129:155644. doi: 10.1016/j.phymed.2024.155644

Müller-Durovic B, Jäger J, Engelmann C, Schuhmachers P, Altermatt S, Schlup Y, Duthaler U, Makowiec C, Unterstab G, Roffeis S, Xhafa E, Assmann N, Trulsson F, Steiner R, Edwards-Hicks J, West J, Turner L, Develioglu L, Ivanek R, Azzi T, Dehio P, Berger C, Swiss Transplant Cohort Study, Kuzmin D, Saboz S, Mautner J, Löliger J, Geigges M, Palianina D, Khanna N, Dirnhofer S, Münz C, Bantug GR, Hess C. A metabolic dependency of EBV can be targeted to hinder B cell transformation. Science. 2024 Jul;385(6704):eadk4898. doi: 10.1126/science.adk4898

Dao K, Buettcher M, Golhen K, Kost J, Schittny A, Duthaler U, Atkinson A, Haefliger D, Guidi M, Bardinet C, Chtioui H, Boulekbache A, Buclin T, Huwyler J, Pfister M, Rothuizen LE. Novel Patient-Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced Palatability, Controlled Absorption, and Less Variability: High Potential for Pediatric Use. J Clin Pharmacol. 2024 Oct;64(10):1295-1303. doi: 10.1002/jcph.2462

Luethi D, Rudin D, Straumann I, Thomann J, Avedisian I, Liechti ME, Duthaler U. Derivatization-free determination of chiral plasma pharmacokinetics of MDMA and its enantiomers. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 May;1238:124123. doi: 10.1016/j.jchromb.2024.124123

Thomann J, Vogt SB, Guessoum A, Meyer M, Vogel M, Liechti ME, Luethi D, Duthaler U. Development and validation of an LC-MS/MS method for quantifying diamorphine and its major metabolites 6-monoacetylmorphine, morphine, morphine-3-glucuronide, and morphine-6-glucuronide in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Apr;1237:124104. doi: 10.1016/j.jchromb.2024.124104

Anliker-Ort M, Rodieux F, Ziesenitz VC, Atkinson A, Bielicki JA, Erb TO, Gürtler N, Holland-Cunz S, Duthaler U, Rudin D, Haschke M, van den Anker J, Pfister M, Gotta V. Pharmacokinetics-Based Pediatric Dose Evaluation and Optimization Using Saliva - A Case Study. J Clin Pharmacol. 2024 Jul;64(7):810-819. doi: 10.1002/jcph.2428

Abegg VF, Panajatovic MV, Mancuso RV, Allard JA, Duthaler U, Odermatt A, Krähenbühl S, Bouitbir J. Mechanisms of hepatocellular toxicity associated with the components of St. John's Wort extract hypericin and hyperforin in HepG2 and HepaRG cells. Toxicol Lett. 2024 Mar;393:1-13. doi: 10.1016/j.toxlet.2024.01.008

Holze F, Erne L, Duthaler U, Liechti ME. Pharmacokinetics, pharmacodynamics and urinary recovery of oral lysergic acid diethylamide administration in healthy participants. Br J Clin Pharmacol. 2024 Jan;90(1):200-208. doi: 10.1111/bcp.15887. PMID: 37596682.
Blukacz L, Nuciforo S, Fucile G, Trulsson F, Duthaler U, Wieland S, Heim MH. Inhibition of the transmembrane transporter ABCB1 overcomes resistance to doxorubicin in patient-derived organoid models of HCC. Hepatol Commun. 2024 May;8(5):e0437. doi: 10.1097/hc9.0000000000000437

Ozbey AC, Bachmann F, Duthaler U, Annaert P, Fowler S, Umehara K, Parrott N, Krähenbühl S. Dose Adjustment in Patients with Liver Cirrhosis - Comparison of Two Different Modeling Approaches. Clin Pharmacol Ther. 2023 Jun;113(6):1346-1358. doi: 10.1002/cpt.2897

Kern C, Müller P, Chaccour C, et al. Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes. Malaria Journal. 2023 Jun;22(1):194. DOI: 10.1186/s12936-023-04624-0